Medical Practice

A Physician-Guided Weight Loss Program Rooted in Hormone Expertise

Hera's weight loss program is led by Dr. Mirela Cernaianu, a board-certified OB/GYN and Menopause Society Certified Practitioner with more than 30 years of clinical experience. She has offered bioidentical hormone therapy in Westlake Village since 2013, and that hormone expertise shapes every weight loss plan she builds.

As a concierge membership practice, Hera Beauty & Wellness has the time that quick-visit weight loss clinics often lack. Extended appointments let Dr. C and her team review your labs, body composition, sleep, and stress together, then adjust your plan every month based on real data. Results are more likely to last after medication is reduced or stopped.

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How GLP-1 and GLP-1/GIP Weight Loss Medications Work

GLP-1 and GLP-1/GIP medications mimic natural gut hormones that help regulate hunger and blood sugar. They work in several ways:

  • Reducing appetite by acting on areas of the brain that control hunger and fullness
  • Slowing stomach emptying, so you feel full sooner and stay full longer
  • Helping the body manage blood sugar by supporting insulin release after meals
  • Lowering overall calorie intake, which leads to gradual weight loss over time

The STEP 1 trial, published in The New England Journal of Medicine, demonstrated the effectiveness of these medications. Adults taking semaglutide 2.4 mg with lifestyle counseling lost an average of 14.9% of their body weight over 68 weeks, compared with 2.4% on placebo.

These medications are not right for everyone, and results vary from person to person. At Hera, medication is considered only after a provider evaluation, and only as one part of a broader plan for your metabolism, hormones, and muscles.

FDA-Approved Weight Loss Medications

Hera Beauty & Wellness prescribes FDA-approved medications such as Wegovy (semaglutide) and Zepbound (tirzepatide) as part of a physician-guided medical weight management program.

The FDA approved Wegovy in 2021 and Zepbound in 2023 for chronic weight management in adults, used alongside a reduced-calorie diet and increased physical activity.

According to the FDA, these medications are approved for adults who have:

  • Obesity, defined as a body mass index (BMI) of 30 or higher, or
  • Overweight, defined as a BMI of 27 or higher, plus at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol

Dr. C reviews your health history, labs, and goals to decide whether an FDA-approved medication is appropriate and which dose to start. Your dose is then adjusted month by month based on side effects, appetite, and your InBody results.

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Customized Compounded Medications

For some patients, a compounded formulation may be considered as part of a personalized treatment plan. Hera prescribes compounded weight loss peptides only after a full provider evaluation.

Compounded medications are not FDA-approved and are prescribed only when a licensed provider determines that a compounded formulation is medically necessary for an individual patient. Medications are compounded and dispensed by a state-licensed pharmacy pursuant to a valid prescription.

If a compounded option is being considered, your provider will walk you through:

  • Why it may or may not suit you, based on your health history, labs, and individual needs
  • How it is dispensed, including the licensed pharmacy that prepares it under your prescription
  • How to use it safely, including dosing instructions and what side effects to watch for
  • How it will be monitored, with your response reviewed at each monthly check-in alongside your InBody results

Like every part of the program, compounded therapy is adjusted or stopped based on how your body responds.

Why GLP-1 Medication Alone Often Isn't Enough for Lasting Weight Loss

GLP-1 medication alone often falls short because it treats appetite, not the reasons why weight was gained. Without testing, monitoring, or a plan for what comes next, progress can stall. Muscle can be lost along with fat, and weight can return once the medication stops.

The STEP 4 trial, published in JAMA, showed this clearly. After 20 weeks on semaglutide, participants who switched to placebo regained an average of 6.9% of their body weight over the next 48 weeks. Those who stayed on the medication lost another 7.9%.

At Hera Beauty & Wellness, weight is a signal of what is happening in your gut, metabolism, hormones, and daily life. Every weight loss program is built on 5 pillars that quick visit weight loss clinics will not offer and often overlook.

The Five Pillars

Pillar 1: Digestive and Metabolic Health

Poor digestive and metabolic health is one of the most common hidden reasons weight loss stalls. When the body is not digesting, absorbing, and processing nutrients well, even a careful diet and effective medication can underperform.

The medical staff at Hera Beauty and Wellness uses a functional medicine approach to evaluate gastrointestinal and metabolic function before and during treatment. Your evaluation may include:

  • A review of digestion, bloating, bowel habits, and food tolerance
  • Metabolic labs that show how your body handles energy
  • A nutrition plan built around what your body needs, especially while your appetite is reduced

Pillar 2: Hormone Optimization, Not Just Hormone Replacement

Hormone optimization means testing and balancing hormones together, not simply prescribing a single patch or cream. An estradiol prescription that controls your hot flashes and improves your symptoms does not equal your hormones are optimized, and it does not mean insulin resistance will improve on its own.

Estrogen in women and testosterone in men both influence insulin sensitivity and body composition. When these hormones decline during perimenopause, menopause, or andropause, fat often collects around the midsection, and weight becomes harder to lose.

Drawing on more than a decade of hormone therapy experience, the medical providers at Hera tests and balances three sex hormones together:

  • Estradiol, which supports insulin sensitivity, metabolism, and body composition
  • Progesterone, which supports sleep, mood, and balance with estrogen
  • Testosterone, in women and men, which supports muscle, energy, and metabolic health

Dosing is adjusted based on your labs, symptoms, and progress. Learn more on our Hormone Therapy page.

Pillar 3: Testing and Correcting Insulin Resistance

Insulin resistance cannot be corrected if it is never measured. TheNational Institute of Diabetes and Digestive and Kidney Diseases explains that insulin resistance develops when cells stop responding well to insulin. Excess weight, especially around the abdomen, is a major contributor.

Hera measures insulin resistance with a comprehensive lab panel at the start of your program and tracks it over time. That way, you know whether a root cause of your weight gain is truly improving.

GLP-1 medications may improve insulin sensitivity while you take them. Hera aims for lasting improvement through hormones, nutrition, strength training, sleep, and stress management. That way, progress is more likely to hold if medication is reduced or stopped.

Pillar 4: Protecting Lean Muscle With Monthly InBody Body Composition Scans

Weight loss isn't always healthy—losing muscle is actually very dangerous. Studies show that lean muscle mass accounts for nearly 40% of the weight lost on GLP-1s like semaglutide (STEP 1 trial substudy*).

You are so much more than a number on a scale. At Hera Beauty and Wellness, we track what truly matters: ensuring your body fat percentage drops while your critical lean muscle is preserved or built.

For adults over 50, that matters. Muscle naturally declines with age and menopause, and losing more muscle increases the risk of weakness, falls, and loss of independence later in life.

Protecting muscle is built into every Hera plan:

  • Monthly InBody scans track lean muscle mass and body fat percentage, not just your weight
  • Monthly plan adjustments to protein targets, strength training, and medication dosing based on scan results
  • Early action if a scan shows muscle loss, before it becomes a setback

Pillar 5: Sleep, Stress, and Longevity: The Big Picture

When weight loss stalls, Hera looks at everything that affects your health, not just your prescription. Our medical providers review includes:

  • Sleep quality and duration
  • Stress and cortisol
  • Diet and eating patterns
  • Hormones
  • Risk factors that affect your longevity
  • Inflammation

Hera practices functional and longevity medicine. Success is measured by your body composition, your strength, how your clothes fit, and how you feel about your results, not only the number on the scale.

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How Hera Beauty & Wellness Keeps Weight Loss Therapy Safe

Every patient on weight-loss medication at Hera is measured, tested, and reviewed monthly. The table below shows what is tracked and why.

Tool

What It Measures

How Often

Why It Matters

InBody body composition scan

Lean muscle mass, body fat %, body water, visceral fat

Monthly

Confirms you are losing fat, not muscle

Insulin resistance score

Fasting insulin, glucose, and related markers

Baseline and follow-up

Shows whether a root cause is improving

Sex hormone panel

Estradiol, progesterone, testosterone

Baseline and as needed

Guides hormone optimization

Metabolic and digestive evaluation

Metabolic labs, thyroid function, lipid panel, inflammation markers, vitamins, digestive function, bone health

Baseline and as needed

Finds hidden barriers to weight loss

Provider check-in

Side effects, appetite and macro tracking, energy, sleep, mood, strength

Monthly

Dose and plan adjusted to you

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Are You a Candidate for Medical Weight Loss?

You may be a good candidate for medical weight loss in Thousand Oaks if you are an adult who:

  • Has tried diets, exercise, or a weight loss medication and feels stuck
  • Noticing weight gain around the midsection, especially during perimenopause, menopause, or andropause
  • Wants to use GLP-1 or GLP-1/GIP therapy without losing muscle or strength
  • Wants a care team with time to listen, test, and follow up personally
  • Did not respond to GLP-1 or GLP-1/GIP therapy, or prefers not to use it
  • Is interested in other peptide therapies as part of a broader plan

Weight loss medications are not safe for everyone. For example, MedlinePlus says people should not use semaglutide if they or a family member has had medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Our medical staff reviews your full history before recommending any medication.

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Why Choose Dr. Cernaianu for Medical Weight Loss in Westlake Village?

Dr. Cernaianu brings a rare combination of OB/GYN training, hormonal expertise, and functional medicine to weight-loss care. Her credentials include:

  • Medical degree from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania
  • OB/GYN residency at Louisiana State University, where she was the first foreign medical graduate admitted to the program
  • Fellowship in Anti-Aging, Regenerative, and Functional Medicine
  • Former Chair of the Obstetrics and Gynecology Department at St. John's Regional Medical Center in Oxnard
  • BioTE pellet therapy trained physician

Patients from across the Conejo Valley also choose Hera for its concierge model. Membership gives you more time with your provider, faster access to appointments, and a team that knows your history. Explore the options on our Medical Memberships page.

What to Expect During Your Medical Weight Loss Program

Hera's program moves from a detailed evaluation to monthly monitoring and, finally, a long-term maintenance plan. Each stage is guided by your labs and scan results.

Consultation

The cost of medical weight loss at Hera in Thousand Oaks depends on your membership tier, the prescribed medication, and how often it is dosed. Pricing is reviewed during your consultation, after your medical provider understands your history and goals.

Hera bills insurance for everything they do, and once a service is not covered, members receive discounted pricing with their membership.

Disclaimer: Compounded medications are not FDA-approved and are prescribed only when a licensed provider determines that a compounded formulation is medically necessary for an individual patient. Medications are compounded and dispensed by a state-licensed pharmacy pursuant to a valid prescription.

Your Program Step by Step

Your program follows five steps:

  1. Comprehensive consultation. A medical provider reviews your history, goals, sleep, stress, diet, and longevity risk factors.
  2. Baseline testing. Comprehensive labs, including your insulin resistance score and sex hormone panel, plus your first InBody scan.
  3. Your personalized plan. Medication if medically appropriate, hormone optimization, nutrition and protein targets, and strength guidance.
  4. Monthly monitoring. An InBody scan and provider check-in, with your plan adjusted based on real data.
  5. Long-term maintenance. A plan to protect your results as medication is reduced, spaced out, or stopped.

Weight Loss Results Timeline and Long-Term Maintenance

Our bodies age every single day. Every 12 months, most people need a structured reset and re-evaluation to maintain their weight loss results—otherwise, the weight will inevitably return. At Hera Beauty and Wellness, we partner with you for year-round, continually monitoring your health to ensure your results are able to last. This is what differenciates Hera compared to other practices.

 Results vary by individual, and no specific amount of weight loss can be guaranteed. In clinical trials, most participants on FDA-approved GLP-1 medications lost 5% or more of their body weight by about one year. In STEP 1, 86.4% of participants taking semaglutide reached that threshold by week 68.

After the first year, Hera's focus shifts to keeping your results. Ongoing InBody scans, hormone checks, and quarterly or monthly check-ins help you hold onto lean muscle and new habits as your plan changes.

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Treatments That Complement Medical Weight Loss

Several Hera treatments can support your weight loss program:

  • EMSCULPT NEO: Combines electromagnetic energy and radiofrequency to build and tone muscle.
  • Hormone Therapy: Bioidentical hormone replacement and optimization for women and men.
  • IV Vitamin Therapy: Delivers nutrients directly into the bloodstream to help prevent deficiencies.
  • Lipotropic Injections: Nutrient injections that may support energy and metabolism.
  • Peptide Therapy: Additional peptides that may be considered as part of a personalized plan.

Medical Weight Loss FAQ

Do GLP-1 Medications Like Semaglutide and Tirzepatide Cause Muscle Loss?

Why Can't I Lose Weight, Even on a GLP-1?

What if I Don't Respond to GLP-1 Therapy?

What Happens When I Stop Taking a GLP-1?

How Can I Maintain Weight Loss Without Medication?

Does Hormone Therapy Help With Weight Loss?

What Are the Side Effects and Risks of Weight Loss Medication?

What Is an InBody Scan?

Is Weight Loss at Hera Only About the Scale?

Do GLP-1 Medications Like Semaglutide and Tirzepatide Cause Muscle Loss?

Yes, they can. In the STEP 1 body composition substudy, lean mass accounted for nearly 40% of the weight lost with semaglutide. Hera tracks your muscle with a monthly InBody scan and adjusts your protein intake, strength training, and dosing to help protect it.

Why Can't I Lose Weight, Even on a GLP-1?

Common hidden causes include undiagnosed insulin resistance, low or suboptimal estrogen or testosterone levels, poor gut or metabolic function, poor sleep, and chronic stress. Dr. C tests and evaluates each of these instead of simply raising your dose.

What if I Don't Respond to GLP-1 Therapy?

Some people lose less weight than expected. In STEP 1, about 14% of participants taking semaglutide did not reach 5% weight loss by week 68. Dr. C looks for underlying causes and may adjust your dose, change medications, or focus on other parts of your plan.

What Happens When I Stop Taking a GLP-1?

Weight often returns after a GLP-1 is stopped, and improvements in insulin sensitivity may fade. In the STEP 4 trial, participants who switched to a placebo regained 6.9% of their body weight over 48 weeks. Hera's program targets root causes, so your results are more likely to last.

How Can I Maintain Weight Loss Without Medication?

Maintaining weight loss without medication depends on far more than calories in and calories out. Genetics, hormones, metabolic rate, sleep, stress, diet, activity, medical conditions, and medications all play a role. Hera's concierge visits allow time to explore each factor and build a maintenance plan around them.

Does Hormone Therapy Help With Weight Loss?

Optimized hormones can support weight loss. Estrogen in women and testosterone in men influence insulin sensitivity and muscle. Dr. C balances estradiol, progesterone, and testosterone together based on your labs, not a one-size-fits-all dose.

What Are the Side Effects and Risks of Weight Loss Medication?

The most common side effects are digestive. In STEP 1, nausea affected 44% of participants on semaglutide; diarrhea, 32%; vomiting, 25%; and constipation, 23%. Most cases were mild to moderate and temporary. Gallbladder problems were also more common. Your provider monitors for side effects at every monthly check-in.

What Is an InBody Scan?

An InBody scan is a quick, non-invasive body composition test that measures muscle mass, body fat percentage, and other markers. Hera repeats it monthly to confirm you are losing fat, not muscle.

Is Weight Loss at Hera Only About the Scale?

No. Hera measures success by body composition, strength, how your clothes fit, and how you feel about your results.

Start Your Medical Evaluation With Dr. C

Lasting weight loss starts with understanding your hormones, metabolism, and muscle. Dr. Cernaianu and the Hera Beauty & Wellness team in Westlake Village will test, measure, and build a plan around you, not just a prescription. Call 805-703-4954 or schedule your consultation online.

Disclaimers:

Compounded medications are not FDA-approved and are prescribed only when a licensed provider determines that a compounded formulation is medically necessary for an individual patient. Medications are compounded and dispensed by a state-licensed pharmacy pursuant to a valid prescription.

This information is provided for educational purposes only and does not replace an evaluation by a licensed medical provider. Weight loss medications are prescribed only when medically appropriate. Outcomes, risks, and suitability vary from patient to patient.


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